anti-AKR1C4 antibody

Arigo Biolaboratories

anti-AKR1C4 antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

AKR1C4

aldo-keto reductase family 1 member C4

3-alpha-HSD; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; aldo-keto reductase family 1 member C4; C11; CDR; CHDR; chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4; DD4; DD-4; dihydrodiol dehydrogenase isozyme DD4; HAKRA; type I 3-alpha-hydroxysteroid dehydrogenase

Goat

IgG

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203