anti-alpha Defensin 1 + alpha Defensin 2 + alpha Defensin 3 antibody
ARG66045
ApplicationsELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetDEFA1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-alpha Defensin 1 + alpha Defensin 2 + alpha Defensin 3 antibody
- Delivery Days Customer23
- ApplicationsELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1667
- Target nameDEFA1
- Target descriptiondefensin alpha 1
- Target synonymsDEF1; DEFA2; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; HNP-1; HP1; HP-1; MRS; myeloid-related sequence; neutrophil defensin 1
- HostGoat
- IsotypeIgG
- Scientific DescriptionDefensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, Oct 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203