Anti-alpha-Gal [Gal13]

Absolute Antibody

Anti-alpha-Gal [Gal13]

9

This antibody is specific for alpha-gal epitopes (Galalpha1-3Galbeta1-4GlcNAc-R) on glycosphingolipids.

This antibody binds to synthetic alpha-gal epitopes linked to BSA and to alpha-gal epitopes on glycolipid molecules from rabbit and bovine erythrocytes (Chen et al, 2000; Galili et al, 1987). However, in contrast to monoclonal anti-Gal antibodies originating from alpha1,3GT knockout mice [M86; B1H2; B4H2], this antibody does not bind to alpha-gal epitopes on carbohydrate chains of natural glycoproteins. This antibody has been used to confirm that Galalphal-3Gal glycosphingolipids are expressed at low levels by human erythrocytes (Galili et al, 1987).

ELISA

Research Use Only

Monoclonal

Gal13

Mouse

IgG1

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.

Bovine, Rabbit

-20°C,2°C to 8°C

12352203