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anti-alpha II Spectrin antibody

Research Use Only
ARG52219
Arigo Biolaboratories
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSPTAN1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-alpha II Spectrin antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID6709
  • Target name
    SPTAN1
  • Target description
    spectrin alpha, non-erythrocytic 1
  • Target synonyms
    alpha-fodrin; alpha-II spectrin; DEE5; EIEE5; epididymis secretory sperm binding protein; fodrin alpha chain; NEAS; spectrin alpha chain, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; SPTA2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (alpha1 and alpha2) and five beta genes (beta1-beta5). Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001). Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis (Eber and Lux 2004).
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203