Anti-alpha Skeletal Muscle Actin Rabbit mAb

PTM BIO

Anti-alpha Skeletal Muscle Actin Rabbit mAb

5

Anti-alpha Skeletal Muscle Actin Rabbit mAb recognizes endogenous level of alpha skeletal muscle actin.

ImmunoPrecipitation, Western Blot

WB, IP

Antibody

Research Use Only

Monoclonal

JMMR-1837C

Unconjugated

Rabbit

IgG

Actin, alpha skeletal muscle

ACTA1 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. ACTA1 is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203