Bio-Connect

anti-AMACR / p504S antibody [Q17-L]

ARG10581
Arigo Biolaboratories
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAMACR
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-AMACR / p504S antibody [Q17-L]
  • Delivery Days Customer
    23
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Q17-L
  • Conjugate
    Unconjugated
  • Gene ID23600
  • Target name
    AMACR
  • Target description
    alpha-methylacyl-CoA racemase
  • Target synonyms
    2-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; AMACRD; CBAS4; P504S; RACE; RM
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203