anti-AMH antibody [AMH41cc]

Arigo Biolaboratories

anti-AMH antibody [AMH41cc]

23

Western Blot, CLIA ChemiLuminecent ImmunoAssay, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Purification/Extraction/Isolation

Research Use Only

Monoclonal

AMH41cc

Unconjugated

AMH

anti-Mullerian hormone

anti-Muellerian hormone; MIF; MIS; muellerian-inhibiting factor; muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance

Mouse

IgG2a

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]

Human

-20°C

12352203