anti-Amyloid Precursor Protein antibody [NT 4A2]

Arigo Biolaboratories

anti-Amyloid Precursor Protein antibody [NT 4A2]

23

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

NT 4A2

Unconjugated

APP

amyloid beta precursor protein

AAA; ABETA; ABPP; AD1; alpha-sAPP; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; amyloid-beta precursor protein; APPI; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; CTFgamma; CVAP; peptidase nexin-II; PN2; PN-II; preA4; protease nexin-II; testicular tissue protein Li 2

Mouse

IgG1

Abeta40, Abeta42 and Abeta43 are different only at the few C-end amino acids. While the C-end amino acids showed no species-specificity in mammalians, the N-terminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Abeta42 and Abeta40 have been investigated extensively for predicating Alzheimers disease. A recent study on A Abeta43 in brain showed that Abeta43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimers disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.

Human

-20°C

12352203