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anti-Angiotensin II + Angiotensin III antibody [Ang II E7 (BGN/KA/4L)]

ARG23505
Arigo Biolaboratories
ApplicationsELISA
Product group Antibodies
ReactivityEquine, Human, Porcine, Rat, Sheep
TargetAGT
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Angiotensin II + Angiotensin III antibody [Ang II E7 (BGN/KA/4L)]
  • Delivery Days Customer
    23
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Ang II E7 (BGN/KA/4L)
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID183
  • Target name
    AGT
  • Target description
    angiotensinogen
  • Target synonyms
    alpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; angiotensinogen; ANHU; fetal-liver predominant transporter 1; hFLT1; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; SERPINA8
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
  • Reactivity
    Equine, Human, Porcine, Rat, Sheep
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203