Anti-APE1

Applied Biological Materials

Anti-APE1

9

APE1 antibody detects endogenous levels of APE1protein. Not tested with other proteins

Western Blot, ELISA

Research Use Only

Polyclonal

Rabbit

IgG

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein

Human

-20°C,2°C to 8°C

12352203