anti-Arrestin 1 / S-Arrestin antibody [S128]
ARG10696
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityBovine
TargetSAG
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Arrestin 1 / S-Arrestin antibody [S128]
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDS128
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID280922
- Target nameSAG
- Target descriptionS-antigen visual arrestin
- Target synonyms48 kDa protein; arrestin1; retinal S-antigen; rod photoreceptor arrestin; S-AG; S-antigen; retina and pineal gland (arrestin); S-arrestin
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]
- ReactivityBovine
- Storage Instruction-20°C
- UNSPSC12352203