anti-ATR phospho (Ser428) antibody
ARG43224
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetATR
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-ATR phospho (Ser428) antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID545
- Target nameATR
- Target descriptionATR serine/threonine kinase
- Target synonymsataxia telangiectasia and Rad3-related protein; FCTCS; FRAP-related protein-1; FRP1; MEC1; MEC1, mitosis entry checkpoint 1, homolog; SCKL; SCKL1; serine/threonine-protein kinase ATR
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203