anti-BAIAP2 antibody

Arigo Biolaboratories

anti-BAIAP2 antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

BAIAP2

BAR/IMD domain containing adaptor protein 2

BAP2, FLAF3, IRSP53, WAML, BAR/IMD domain-containing adapter protein 2, BAI1 associated protein 2, IRS-58, IRSp53/58, WASP and MIM like, brain-specific angiogenesis inhibitor 1-associated protein 2, fas ligand-associated factor 3, insulin receptor substrate of 53 kDa, insulin receptor substrate p53/p58, insulin receptor substrate protein of 53 kDa

Goat

IgG

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

-20°C

12352203