Western Blot: Human Brain lysate (RIPA buffer, 35 microg total protein per lane) stained with ARG63536 anti-BAIAP2 (isoform 1) antibody at 1 microg/ml dilution.
Western Blot: Human Brain lysate (RIPA buffer, 35 microg total protein per lane) stained with ARG63536 anti-BAIAP2 (isoform 1) antibody at 1 microg/ml dilution.
anti-BAIAP2 antibody
ARG63536
TargetBAIAP2
Product group Antibodies
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-BAIAP2 antibody
- Delivery Days Customer23
- Concentration0.5 mg/ml
- Gene ID10458
- Target nameBAIAP2
- Target descriptionBAR/IMD domain containing adaptor protein 2
- Target synonymsBAI1 associated protein 2; BAP2; brain-specific angiogenesis inhibitor 1-associated protein 2; fas ligand-associated factor 3; FLAF3; insulin receptor substrate of 53 kDa; insulin receptor substrate p53/p58; insulin receptor substrate protein of 53 kDa; IRS-58; IRSP53; IRSp53/58; WAML; WASP and MIM like
- Scientific DescriptionThe protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
- Storage Instruction-20°C
- UNSPSC12352203