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anti-Bak antibody

Research Use Only
ARG63187
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Rat
TargetBAK1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Bak antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID578
  • Target name
    BAK1
  • Target description
    BCL2 antagonist/killer 1
  • Target synonyms
    apoptosis regulator BAK; BAK; BAK-LIKE; bcl-2 homologous antagonist/killer; BCL2L7; bcl2-L-7; BCL2-like 7 protein; bcl-2-like protein 7; CDN1; pro-apoptotic protein BAK
  • Host
    Goat
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Porcine, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203