anti-Bcl 2 phospho (Ser70) antibody
ARG51568
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetBCL2
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Bcl 2 phospho (Ser70) antibody
- Delivery Days Customer23
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID596
- Target nameBCL2
- Target descriptionBCL2 apoptosis regulator
- Target synonymsapoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; Bcl-2; PPP1R50; protein phosphatase 1, regulatory subunit 50
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203