anti-Bestrophin antibody
ARG10776
ApplicationsDot Blot, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application
Product group Antibodies
ReactivityHuman
TargetBEST1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Bestrophin antibody
- Delivery Days Customer23
- ApplicationsDot Blot, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID7439
- Target nameBEST1
- Target descriptionbestrophin 1
- Target synonymsARB; BEST; Best disease; Best1V1Delta2; bestrophin-1; BMD; RP50; TU15B; vitelliform macular dystrophy protein 2; VMD2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203