anti-beta Amyloid (1 - 40) antibody [CV9 7B10]
ARG11087
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetAPP
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-beta Amyloid (1 - 40) antibody [CV9 7B10]
- Delivery Days Customer23
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCV9 7B10
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID351
- Target nameAPP
- Target descriptionamyloid beta precursor protein
- Target synonymsAAA; ABETA; ABPP; AD1; alpha-sAPP; alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid precursor protein; amyloid-beta precursor protein; APPI; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; cerebral vascular amyloid peptide; CTFgamma; CVAP; peptidase nexin-II; PN2; PN-II; preA4; protease nexin-II; testicular tissue protein Li 2
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203