Anti-beta catenin [15B8]

Absolute Antibody

Anti-beta catenin [15B8]

9

This antibody recognizes beta catenin. It does not react with plakoglobin. beta-Catenin plays a dual function in the cell including cell-cell adhesion and as a component of the Wnt (wingless) signaling pathway.

This antibody is recommended for the detection and analysis of beta-catenin via various methods, such as Western blot, flow cytometry and immunofluorescence of cells and tissues. For instance, the antibody 15B8 was utilized in labelling beta-catenin in oral mucosa samples via immunohistochemistry (Das et al., 2013). Another group used this antibody in the identification of beta-catenin in extracts from K562 cells via Western blots (Kotula et al., 2014). Furthermore, this antibody was applied during immunohistochemistry stainings of transverse sections taken through the midbrain region of 8-9ss embryos (Schiffmacher et al., 2016). Finally,beta-catenin is a very popular marker used to outline the cell membrane, this antibody might be utilized for such purposes (Zhang et al., 2017).

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

15B8

CTNNB1

catenin beta 1

armadillo; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; EVR7; MRD19; NEDSDV

Rabbit

IgG

Catenin beta-1

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Bovine, Canine, Chicken, Human, Mouse, Rat

-20°C,2°C to 8°C

12352203