Western blot: C6 cell lysate stained with ARG57638 anti-beta Catenin phospho (Ser675) antibody. Cells were untreated (left) or treated by CIP (right).
Western blot: C6 cell lysate stained with ARG57638 anti-beta Catenin phospho (Ser675) antibody. Cells were untreated (left) or treated by CIP (right).
anti-beta Catenin phospho (Ser675) antibody
ARG57638
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetCTNNB1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-beta Catenin phospho (Ser675) antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1499
- Target nameCTNNB1
- Target descriptioncatenin beta 1
- Target synonymsarmadillo; catenin (cadherin-associated protein), beta 1, 88kDa; catenin beta-1; CTNNB; EVR7; MRD19; NEDSDV
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203