anti-BIRC7 / LIVIN antibody

Arigo Biolaboratories

anti-BIRC7 / LIVIN antibody

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

BIRC7

baculoviral IAP repeat containing 7

baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; LIVIN; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; MLIAP; ML-IAP; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; RNF50

Goat

IgG

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203