Anti-BMP receptor type IA [AbD1556]

Absolute Antibody

Anti-BMP receptor type IA [AbD1556]

9

The antibody binds to human BMPR-IA with a low nanomolar affinity.

This antibody binds to human BMPR-1A, which, on ligand bindingg, forms a receptor complex acting as a serine/threonine kinase, activating SMAD transcriptional regulators. They positively regulate chondrocyte differentiation, for example. The antibody neutralizes BMP-binding to the receptor.

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

AbD1556

BMPR1A

bone morphogenetic protein receptor type 1A

10q23del; activin A receptor, type II-like kinase 3; activin receptor-like kinase 3; ACVRLK3; ALK3; ALK-3; BMP type-1A receptor; BMPR-1A; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type IA; CD292; serine/threonine-protein kinase receptor R5; SKR5

Mouse

IgG2a

Bone morphogenetic protein receptor type-1A

Human

-20°C,2°C to 8°C

12352203