Anti-Butyryl-Histone H3 (Lys14) Rabbit mAb

PTM BIO

Anti-Butyryl-Histone H3 (Lys14) Rabbit mAb

5

Anti-Butyryl-Histone H3 (Lys14) Rabbit mAb detects histone H3 only when it is butyrylated at Lys14.

ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry

WB, ICC/IF, ChIP

Antibody

Research Use Only

Monoclonal

PA-039-24BH0L0

Unconjugated

Rabbit

IgG

Histone H3.1

H3 is core component of nucleosome. Nucleosomes wrap and compact DNAinto chromatin, limiting DNA accessibility to the cellular machineries whichrequire DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histones are subjected to a variety of enzyme catalyzed modifications, including acetylation, methylation, Phosphorylatedrylation, ubiquitylation, etc. Butyrylation of histones marks active promoters and competes with histone acetylation, which occurs during late

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203