anti-Caspase 11 antibody

Arigo Biolaboratories

anti-Caspase 11 antibody

23

ImmunoPrecipitation, Western Blot

Research Use Only

Polyclonal

Unconjugated

Casp4

caspase 4, apoptosis-related cysteine peptidase

Cas; Casp11; CASP-11; CASP-4; Caspa; caspase 11, apoptosis-related cysteine peptidase; caspase 11, apoptosis-related cysteine protease; caspase 4, apoptosis-related cysteine protease; caspase-11 short form splicing; caspase-4; Caspl; ich-; ich-3; protease ICH-3

Rabbit

IgG

This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is caspase 4, apoptosis-related cysteine peptidase, this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]

Mouse

-20°C

12352203