Anti-Caspase 4

Applied Biological Materials

Anti-Caspase 4

9

Caspase 4 antibody detects endogenous levels of Caspase 4 protein. Not tested with other proteins

Western Blot, ELISA

Research Use Only

Polyclonal

Rabbit

IgG

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Human

-20°C,2°C to 8°C

12352203