anti-Cathepsin B antibody
ARG10664
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCTSB
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Cathepsin B antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID1508
- Target nameCTSB
- Target descriptioncathepsin B
- Target synonymsamyloid precursor protein secretase; APP secretase; APPS; cathepsin B; cathepsin B1; CPSB; cysteine protease; epididymis secretory sperm binding protein; RECEUP
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203