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anti-Cathepsin B antibody

ARG10664
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCTSB
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Cathepsin B antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1508
  • Target name
    CTSB
  • Target description
    cathepsin B
  • Target synonyms
    amyloid precursor protein secretase; APP secretase; APPS; cathepsin B; cathepsin B1; CPSB; cysteine protease; epididymis secretory sperm binding protein; RECEUP
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203