Anti-Cavbeta1 Ca2+ channel [N7/18.1]

Absolute Antibody

Anti-Cavbeta1 Ca2+ channel [N7/18.1]

7

This antibody is specific for the Cav1 protein, regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity).

The IgG2a version of this antibody was used for immunofluorescence on primary myoblasts from 1-null muscles (5, 9) infected with 1a cDNA-containing virions at a multiplicity of infection of 0.5 (Eltit et al, 2014; PMID:25384984). Immunoprecipitation has been preformed on HEK293 cell lysates using the IgG2a version of this antibody (Morgenstern et al, 2019; PMID:31403402). This antibody has been used for immunofluorescence on mouse hippocampal cultures (Held et al, 2020; PMID:32616470). Immunoprecipitation was preformed with this antibody on the lysate of mouse hemibrains ( Voskobiynyk, 2020; PMID:32657270). This antibody was used in immunoblotting of myoblasts stably transduced with Wt-beta1a or beta1a-V156A subunit (Perez, 2018; PMID:29212769). Immunofluorescence was preformed on mouse diaphraghms by using this antibody (Kaplan et al, 2018; PMID:29949772).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot

IF; WB; IP

Research Use Only

Monoclonal

N7/18.1

Cacnb1

calcium voltage-gated channel auxiliary subunit beta 1

brain calcium channel beta 1 subunit; CAB1; calcium channel beta 1 subunit; calcium channel voltage-dependent subunit beta 1; calcium channel, voltage-dependent, beta 1 subunit; voltage-dependent L-type calcium channel subunit beta-1

Rat

IgG2b

Voltage-dependent L-type calcium channel subunit beta-1

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse, Rat

human, mouse, rat

This antibody was raised by immunising BALB/c mice with a synthetic peptide of amino acids 19-34 of rat Cav1.

-20°C,2°C to 8°C

12352203