Anti-Caveolin-1 Mouse mAb

PTM BIO

Anti-Caveolin-1 Mouse mAb

5

Western Blot

WB

Antibody

Research Use Only

Monoclonal

11403

Unconjugated

Mouse

IgG

Caveolin-1

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Human, Mouse

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203