anti-CBR1 antibody

Arigo Biolaboratories

anti-CBR1 antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

1.3 mg/ml

Unconjugated

CBR1

carbonyl reductase 1

15-hydroxyprostaglandin dehydrogenase; 20-beta-hydroxysteroid dehydrogenase; carbonyl reductase (NADPH) 1; carbonyl reductase [NADPH] 1; CBR; epididymis secretory sperm binding protein; hCBR1; NADPH-dependent carbonyl reductase 1; PG-9-KR; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase; SDR21C1; short chain dehydrogenase/reductase family 21C member 1

Mouse

IgG1

NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.

Human

-20°C

12352203