anti-CBX1 / HP1 beta antibody [MAC353]

Arigo Biolaboratories

anti-CBX1 / HP1 beta antibody [MAC353]

23

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

MAC353

Unconjugated

Cbx1

chromobox 1

Cbx; Cbx-r; Cbx-rs2; chromobox homolog 1; chromobox protein homolog 1; E430007M08Rik; heterochromatin protein 1 homolog beta; heterochromatin protein p25; HP1; HP1B; Hp1be; Hp1beta; M31; MOD; MOD1; modifier 1 protein

Rat

IgG2b

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Mouse

-20°C

12352203