Anti-CD106 [B-K9 (C106-K9)]

Absolute Antibody

Anti-CD106 [B-K9 (C106-K9)]

9

B-K9 antibody recognizes CD106 (VCAM1). CD106 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal trans

B-K9 antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells, and thus it blocks the ability of white blood cells to attach themselves to the activated epithelium during, for instance, inflammation. Consequently, this antibody might be used in research where leukocytes adhesion-blocking is required (Uotila et al., 2014; Wagner et al. 2011).

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

B-K9 (C106-K9)

VCAM1

vascular cell adhesion molecule 1

CD106; CD106 antigen; INCAM-100; vascular cell adhesion protein 1

Human

IgG1

Vascular cell adhesion protein 1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203