Anti-CD11a [hu1124 (Efalizumab)]
Ab00535-1.1
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetITGAL
Overview
- SupplierAbsolute Antibody
- Product NameAnti-CD11a [hu1124 (Efalizumab)]
- Delivery Days Customer7
- Antibody SpecificityBinds to human LFA-1.
- Application Supplier NoteEfalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
- ApplicationsFlow Cytometry, Neutralisation/Blocking
- Applications SupplierBlock; FC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDhu1124 (Efalizumab)
- Gene ID3683
- Target nameITGAL
- Target descriptionintegrin subunit alpha L
- Target synonymsantigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11A; integrin alpha-L; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1, alpha polypeptide
- HostMouse
- IsotypeIgG1
- Protein IDP20701
- Protein NameIntegrin alpha-L
- Scientific DescriptionThis chimeric murine antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteEfalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203