anti-CD11b antibody [CC126]
ARG23375
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityBovine
TargetITGAM
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD11b antibody [CC126]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCC126
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID407124
- Target nameITGAM
- Target descriptionintegrin subunit alpha M
- Target synonymsCD11B; integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); leukocyte integrin alpha-M chain
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionCD11b (integrin alpha M chain): Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- ReactivityBovine
- Storage Instruction-20°C
- UNSPSC12352203