anti-CD11b antibody [ED8]
ARG23481
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityRat
TargetItgam
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD11b antibody [ED8]
- Delivery Days Customer23
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDED8
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID25021
- Target nameItgam
- Target descriptionintegrin subunit alpha M
- Target synonymsCd11b; integrin alpha-M; integrin, alpha M
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD11b (integrin alpha M chain): Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- ReactivityRat
- Storage Instruction-20°C
- UNSPSC12352203