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anti-CD123 / IL3RA antibody

Research Use Only
ARG40371
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetIL3RA
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD123 / IL3RA antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3563
  • Target name
    IL3RA
  • Target description
    interleukin 3 receptor subunit alpha
  • Target synonyms
    CD123; CD123 antigen; hIL-3Ra; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203