anti-CD129 / IL9R antibody [AH9R7] (low endotoxin)

Arigo Biolaboratories

anti-CD129 / IL9R antibody [AH9R7] (low endotoxin)

23

Functional Assay, Flow Cytometry, ELISA

Research Use Only

Monoclonal

AH9R7

1 mg/ml

Unconjugated

IL9R

interleukin 9 receptor

CD129; IL-9 receptor; IL-9R; interleukin-9 receptor

Mouse

IgG2b

The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203