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anti-CD13 antibody [R3-63] (PE)

Research Use Only
ARG22994
Arigo Biolaboratories
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetAnpep
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD13 antibody [R3-63] (PE)
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    R3-63
  • Conjugate
    RPE
  • Gene ID16790
  • Target name
    Anpep
  • Target description
    alanyl (membrane) aminopeptidase
  • Target synonyms
    alanyl aminopeptidase; aminopeptidase M; aminopeptidase N; aminopeptidase N/CD13; AP-M; Apn; AP-N; Cd13; membrane protein p161; microsomal aminopeptidase; P150
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203