anti-CD137 antibody [4B4-1] (PE)
ARG42273
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetTNFRSF9
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD137 antibody [4B4-1] (PE)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4B4-1
- ConjugateRPE
- Gene ID3604
- Target nameTNFRSF9
- Target descriptionTNF receptor superfamily member 9
- Target synonyms4-1BB; 4-1BB ligand receptor; CD137; CD137 antigen; CDw137; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; T cell antigen ILA; T-cell antigen 4-1BB homolog; tumor necrosis factor receptor superfamily member 9
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203