anti-CD138 / Syndecan 1 antibody [B-A38] (azide free)
ARG65410
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityGuinea Pig, Human, Rat
TargetSDC1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD138 / Syndecan 1 antibody [B-A38] (azide free)
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB-A38
- Concentration1 mg/ml
- ConjugateUnconjugated
- Estimated Purity>95%
- Gene ID6382
- Target nameSDC1
- Target descriptionsyndecan 1
- Target synonymsCD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; SDC; SYND1; syndecan; syndecan proteoglycan 1; syndecan-1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
- ReactivityGuinea Pig, Human, Rat
- Storage Instruction-20°C
- UNSPSC12352203