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anti-CD152 / CTLA4 antibody [1B8]

ARG21001
Arigo Biolaboratories
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityMouse
TargetCtla4
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-CD152 / CTLA4 antibody [1B8]
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1B8
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID12477
  • Target name
    Ctla4
  • Target description
    cytotoxic T-lymphocyte-associated protein 4
  • Target synonyms
    Cd152; CD152 antigen; Ctla; Ctla-4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte-associated antigen 4; Ly-5; Ly-56
  • Host
    Hamster
  • Isotype
    IgG1
  • Scientific Description
    This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203