anti-CD152 / CTLA4 antibody [WKH203]

Arigo Biolaboratories

anti-CD152 / CTLA4 antibody [WKH203]

23

Flow Cytometry, Western Blot, ELISA

Research Use Only

Monoclonal

WKH203

1 mg/ml

Unconjugated

Ctla4

cytotoxic T-lymphocyte-associated protein 4

Cd152; CD152 antigen; CTLA-4; cytotoxic T-lymphocyte protein 4; sCTLA4; soluble form; transmembrane form

Mouse

IgG1

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Rat

-20°C

12352203