Anti-CD155 [CD155.16 ]

Absolute Antibody

Anti-CD155 [CD155.16 ]

9

This antibody binds human CD155 also called the poliovirus receptor (PVR). The binding of this antibody does not block binding of TIGIT to CD155/PVR. This protein mediates NK cell adhesion and triggers NK cell function. It also binds two NK cell receptors

This antibody was used to identify CD155 expression on U-87 MG and U-87 MG PVRhi cell lines using flow cytometry. This antibody was used in the generation of anti-CD155 -saporin and anti-CD155-diphtheria immunotoxins and were tested for its antitumor activity. Cytotoxic effect was determined by ToxiLight kit. The results suggested that the immunotoxins were successful in killing CD155 expressing tumor cells.(WO2019102456).

Flow Cytometry

Research Use Only

Monoclonal

CD155.16

PVR

PVR cell adhesion molecule

CD155; HVED; NECL5; Necl-5; nectin-like protein 5; poliovirus receptor; PVS; TAGE4

Rabbit

IgG

Poliovirus receptor

Human

-20°C,2°C to 8°C

12352203