Anti-CD172A/SIRPA [OX-41]

Absolute Antibody

Anti-CD172A/SIRPA [OX-41]

7

This antibody binds to rat SIRP alpha, which is selectively expressed by myeloid and neuronal cells.

This antibody binds to SIRP alpha, and can consequently be used to label neuronal cells and myeloid cells, namely macrophages, monocytes, granulocutes and dendritic cells, in immunofluorescence and immunohistochemical studies (Robinson, 1986). Anti-SIRP ligation induces nitric oxide synthesis and oxidative burst in macrophages (Adams, 1998).

Functional Assay, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

WB; ELISA; IHC; IF; IP; functional

Research Use Only

Monoclonal

OX-41

Sirpa

signal-regulatory protein alpha

Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; CD172 antigen-like family member A; inhibitory receptor SHPS-1; macrophage fusion receptor; macrophage membrane protein MFP150; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHPS-1; signal-regulatory protein alpha-1; sirp-alpha-1; tyrosine-protein phosphatase non-receptor type substrate 1

Rat

IgG2b

Tyrosine-protein phosphatase non-receptor type substrate 1

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Rat

Rat

Rat resident peritoneal cells injected into BALB/c mice.

-20°C,2°C to 8°C

12352203