anti-CD177 antibody [MEM-166] (APC)
ARG53776
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetCD177
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD177 antibody [MEM-166] (APC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-166
- ConjugateAPC (Allophycocyanin)
- Gene ID57126
- Target nameCD177
- Target descriptionCD177 molecule
- Target synonymsCD177 antigen; cell surface receptor; HNA2A; HNA-2a; human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; polycythemia rubra vera protein 1; PRV1; PRV-1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203