anti-CD177 antibody [MEM-166]

Arigo Biolaboratories

anti-CD177 antibody [MEM-166]

23

Flow Cytometry, ImmunoPrecipitation, Western Blot, Other Application

Research Use Only

Monoclonal

MEM-166

1 mg/ml

Unconjugated

>95%

CD177

CD177 molecule

CD177 antigen; cell surface receptor; HNA2A; HNA-2a; human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; polycythemia rubra vera protein 1; PRV1; PRV-1

Mouse

IgG1

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Human

-20°C

12352203