anti-CD1b + CD1c antibody [B-B5] (FITC)

Arigo Biolaboratories

anti-CD1b + CD1c antibody [B-B5] (FITC)

23

Flow Cytometry

Research Use Only

Monoclonal

B-B5

FITC

CD1B

CD1b molecule

CD1; CD1A; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; R1; T-cell surface glycoprotein CD1b

Mouse

IgG1

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C

12352203