Anti-CD2 [OX-34]

Absolute Antibody

Anti-CD2 [OX-34]

7

OX-34 binds specifically to rat CD2. CD2 is type I membrane protein involved in triggering of T-cells (cytoplasmic domain is involved in signaling function) and is expressed on thymocytes, peripheral T cells, dendritic epidermal T cells, macrophages in th

Ox34 blocks CD48 binding to CD2 causing partial block of T cell activation; OX34 can be used to deplete peripheral T cells (used to prevent allograft rejection in vivo).

Flow Cytometry, Neutralisation/Blocking

block; FC

Research Use Only

Monoclonal

OX-34

Cd2

Cd2 molecule

CD2 antigen; CD2R; LFA2; LFA-2; LFA-3 receptor; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Rat

IgG2b

T-cell surface antigen CD2

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Rat

Rat

OX-34 was prepared by immunizing mice with T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen.

-20°C,2°C to 8°C

12352203