anti-CD205 antibody [HD30] (PE)

Arigo Biolaboratories

anti-CD205 antibody [HD30] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

HD30

RPE

LY75

lymphocyte antigen 75

CD205; CLEC13B; C-type lectin domain family 13 member B; DEC-205; GP200-MR6; LY-75; lymphocyte antigen 75

Mouse

IgG1

CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.

Human

2°C to 8°C

12352203