Anti-CD21L [R4/23]

Absolute Antibody

Anti-CD21L [R4/23]

7

This antibody recognises CD21L which is a long isoform of CD21 (CR2) (with an additional exon 10a). It is strongly expressed on dendritic reticulum cells and serves as a receptor for the complement elements (and is also bound by EBV).

CD21L is strongly expressed in reticulum dendritic cells and R4/23 might be used for the identification of these cells. For instance, Schriever et al. (1989) used this antibody (among others) in an attempt to differentiate follicular dendritic cells from lymphoid dendritic cells. This antibody can be also utilised in the characterisation of certain cancers; for example, one group used it in an immunohistochemical analysis of frozen samples of tumour cells from diffuse large B-cell lymphoma (Ogawa et al., 2004).

Western Blot, ImmunoHistoChemistry

IHC; WB

Research Use Only

Monoclonal

R4/23

CR2

complement C3d receptor 2

C3DR; CD21; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor type 2; CR; CVID7; EBV receptor; SLEB9

Rabbit

IgG

Complement receptor type 2

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

This antibody was raised by immunising BALB/c mice with C3 receptor-coated erythrocytes.

-20°C,2°C to 8°C

12352203