Bio-Connect

Anti-CD22 [LL2 (EPB2)]

Research Use Only
Ab01486-10.0
Absolute Antibody
ApplicationsFlow Cytometry, ImmunoHistoChemistry, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
TargetCD22
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD22 [LL2 (EPB2)]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody recognises CD22, which is a cytoplasmic molecule expressed in progenitor and early-pre B cells.
  • Application Supplier Note
    This antibody has been used in research on the diagnosis and treatment of non-Hodgkins B cell lymphoma. Specificity to B-cell line of the LL2 (EPB-2) antibody was confirmed by radioimmunobinding and flow cytometry, where it did not bind to any other targets, such as T cells and normal diploid cells at the same time labelling malignant lymphoma tissue (Pawlak-Byczkowska et al., 1989).
  • Applications
    Flow Cytometry, ImmunoHistoChemistry, RadioImmunoAssay
  • Applications Supplier
    RIA; FC; IHC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    LL2 (EPB2)
  • Gene ID933
  • Target name
    CD22
  • Target description
    CD22 molecule
  • Target synonyms
    B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDP20273
  • Protein Name
    B-cell receptor CD22
  • Scientific Description
    This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    This antibody was raised by immunising Balb/c mice with Raji cells or a fragmented cell mixture.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203