Anti-CD22 [LL2 (EPB2)]

Absolute Antibody

Anti-CD22 [LL2 (EPB2)]

7

This antibody recognises CD22, which is a cytoplasmic molecule expressed in progenitor and early-pre B cells.

This antibody has been used in research on the diagnosis and treatment of non-Hodgkins B cell lymphoma. Specificity to B-cell line of the LL2 (EPB-2) antibody was confirmed by radioimmunobinding and flow cytometry, where it did not bind to any other targets, such as T cells and normal diploid cells at the same time labelling malignant lymphoma tissue (Pawlak-Byczkowska et al., 1989).

Flow Cytometry, ImmunoHistoChemistry, RadioImmunoAssay

RIA; FC; IHC

Research Use Only

Monoclonal

LL2 (EPB2)

CD22

CD22 molecule

B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14

Human

IgG4

B-cell receptor CD22

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

This antibody was raised by immunising Balb/c mice with Raji cells or a fragmented cell mixture.

-20°C,2°C to 8°C

12352203